Transcriptional Silencing by Hairpin RNAs Complementary to a Gene Promoter

Double-stranded RNAs can target gene promoters and inhibit transcription. To date, most research has focused on synthetic RNA duplexes. Transcriptional silencing by hairpin RNAs would facilitate a better understanding of endogenous RNA-mediated regulation of transcription within cells. Here we exami...

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Autori principali: Chu, Yongjun, Kalantari, Roya, Dodd, David W., Corey, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871491/
https://ncbi.nlm.nih.gov/pubmed/22703280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0360
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