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Obese and diabetic KKAy mice show increased mortality but improved cardiac function following myocardial infarction
BACKGROUND: Introduction of the yellow obese gene (A(y)) into mice (KKAy) results in obesity and diabetes by 5 weeks of age. METHODS: Using this model of type 2 diabetes, we evaluated male and female 6–8 month old wild type (WT, n=10) and KKAy (n=22) mice subjected to myocardial infraction (MI) and...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965668/ https://ncbi.nlm.nih.gov/pubmed/23896047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2013.06.002 |
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