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Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche()
Autoantibodies to double-stranded DNA (dsDNA), produced by auto-reactive plasma cells (PC), are a hallmark of systemic lupus erythematosus (SLE) and play a key role in disease pathogenesis. Recent data suggests that auto-reactive PC accumulate not only in lymphoid tissues but also in the inflamed ki...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965596/ https://ncbi.nlm.nih.gov/pubmed/24574498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302003 |
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