Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response

Although B cell depletion therapy (BCDT) is effective in a subset of rheumatoid arthritis (RA) patients, both mechanisms and biomarkers of response are poorly defined. Here we characterized abnormalities in B cell populations in RA and the impact of BCDT in order to elucidate B cell roles in the dis...

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Vydáno v:PLoS One
Hlavní autoři: Adlowitz, Diana G., Barnard, Jennifer, Biear, Jamie N., Cistrone, Christopher, Owen, Teresa, Wang, Wensheng, Palanichamy, Arumugam, Ezealah, Ezinma, Campbell, Debbie, Wei, Chungwen, Looney, R. John, Sanz, Inaki, Anolik, Jennifer H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457888/
https://ncbi.nlm.nih.gov/pubmed/26047509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128269
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