Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice

BACKGROUND & AIMS: High mobility group box 1 (HMGB1) is an abundant protein that regulates chromosome architecture and also functions as a damage-associated molecular pattern molecule. Little is known about its intracellular roles in response to tissue injury or during subsequent local and syste...

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Autors principals: Kang, Rui, Zhang, Qiuhong, Hou, Wen, Yan, Zhenwen, Chen, Ruochan, Bonaroti, Jillian, Bansal, Preeti, Billiar, Timothy R., Tsung, Allan, Wang, Qingde, Bartlett, David L., Whitcomb, David C, Chang, Eugene B., Zhu, Xiaorong, Wang, Haichao, Lu, Ben, Tracey, Kevin J., Cao, Lizhi, Fan, Xue-Gong, Lotze, Michael T., Zeh, Herbert J., Tang, Daolin
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965592/
https://ncbi.nlm.nih.gov/pubmed/24361123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.12.015
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