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HMGB1 Controls Liver Cancer Initiation through YAP-dependent Aerobic Glycolysis

Emerging studies have suggested that the Hippo pathway is involved in the tumorigenesis of hepatocellular carcinoma (HCC). However, the key regulator of the Hippo pathway in liver tumor metabolic reprogramming remains elusive. Here, we provide evidence to support that high mobility group box 1 (HMGB...

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Vydáno v:Hepatology
Hlavní autoři: Chen, Ruochan, Zhu, Shan, Fan, Xue-Gong, Wang, Haichao, Lotze, Michael T., Zeh, Herbert J., Billiar, Timothy R., Kang, Rui, Tang, Daolin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906197/
https://ncbi.nlm.nih.gov/pubmed/29149457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29663
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