The Lymphocytosis-Promoting Agent Pertussis Toxin Affects Virus Burden and Lymphocyte Distribution in the SIV-Infected Rhesus Macaque

Pertussis toxin from the gram-negative bacterium Bordetella pertussis is an ADP-ribosylase that modifies G(i) proteins in mammalian lymphocytes and inhibits their capacity to traffic from blood into lymphoid tissues. We used this compound to induce lymphocytosis in rhesus macaques and to study its e...

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Bibliografiska uppgifter
Huvudupphovsmän: Pauza, C. David, Hinds, Paul W., Yin, Cheng, McKechnie, Timothy S., Hinds, Sarah B., Salvato, Maria S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 1997
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965356/
https://ncbi.nlm.nih.gov/pubmed/8989431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.1997.13.87
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