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The Lymphocytosis-Promoting Agent Pertussis Toxin Affects Virus Burden and Lymphocyte Distribution in the SIV-Infected Rhesus Macaque
Pertussis toxin from the gram-negative bacterium Bordetella pertussis is an ADP-ribosylase that modifies G(i) proteins in mammalian lymphocytes and inhibits their capacity to traffic from blood into lymphoid tissues. We used this compound to induce lymphocytosis in rhesus macaques and to study its e...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc.
1997
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965356/ https://ncbi.nlm.nih.gov/pubmed/8989431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.1997.13.87 |
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