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Stalled replication fork repair and misrepair during thymineless death in Escherichia coli

Starvation for DNA precursor dTTP, known as ‘thymineless death’ (TLD), kills bacterial and eukaryotic cells alike. Despite numerous investigations, toxic mechanisms behind TLD remain unknown, although wrong nucleotide incorporation with subsequent excision dominates the explanations. We show that ki...

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Bibliografiska uppgifter
Huvudupphovsmän: Kuong, Kawai J, Kuzminov, Andrei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965187/
https://ncbi.nlm.nih.gov/pubmed/20465561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2010.01405.x
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