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Stalled replication fork repair and misrepair during thymineless death in Escherichia coli
Starvation for DNA precursor dTTP, known as ‘thymineless death’ (TLD), kills bacterial and eukaryotic cells alike. Despite numerous investigations, toxic mechanisms behind TLD remain unknown, although wrong nucleotide incorporation with subsequent excision dominates the explanations. We show that ki...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965187/ https://ncbi.nlm.nih.gov/pubmed/20465561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2010.01405.x |
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