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Role of DNA Replication and Repair in Thymineless Death in Escherichia coli

Inhibition of DNA replication with hydroxyurea during thymine starvation of Escherichia coli shows that active DNA synthesis is not required for thymineless death (TLD). Hydroxyurea experiments and thymine starvation of lexA3 and uvrA DNA repair mutants rule out unbalanced growth, the SOS response,...

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Detalhes bibliográficos
Main Authors: Morganroth, Pamela A., Hanawalt, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539979/
https://ncbi.nlm.nih.gov/pubmed/16816201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00543-06
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