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Role of DNA Replication and Repair in Thymineless Death in Escherichia coli

Inhibition of DNA replication with hydroxyurea during thymine starvation of Escherichia coli shows that active DNA synthesis is not required for thymineless death (TLD). Hydroxyurea experiments and thymine starvation of lexA3 and uvrA DNA repair mutants rule out unbalanced growth, the SOS response,...

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Main Authors: Morganroth, Pamela A., Hanawalt, Philip C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539979/
https://ncbi.nlm.nih.gov/pubmed/16816201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00543-06
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