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Role of DNA Replication and Repair in Thymineless Death in Escherichia coli

Inhibition of DNA replication with hydroxyurea during thymine starvation of Escherichia coli shows that active DNA synthesis is not required for thymineless death (TLD). Hydroxyurea experiments and thymine starvation of lexA3 and uvrA DNA repair mutants rule out unbalanced growth, the SOS response,...

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Bibliographische Detailangaben
Hauptverfasser: Morganroth, Pamela A., Hanawalt, Philip C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539979/
https://ncbi.nlm.nih.gov/pubmed/16816201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00543-06
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