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Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer

A major challenge affecting the outcomes of patients with lung cancer is the development of acquired radioresistance. However, the mechanisms underlying the development of resistance to therapy are not fully understood. Here we discovered that ionizing radiation (IR) induces phosphorylation of JAK2...

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Dettagli Bibliografici
Autori principali: You, Shuo, Li, Rui, Park, Dongkyoo, Xie, Maohua, Sica, Gabriel L., Cao, Ya, Xiao, Zhi-Qiang, Deng, Xingming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964811/
https://ncbi.nlm.nih.gov/pubmed/24362463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0608
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