Caricamento...
IL-12(hi) Rapamycin-Conditioned Dendritic Cells Mediate IFN-γ—Dependent Apoptosis of Alloreactive CD4(+) T Cells In Vitro and Reduce Lethal Graft-Versus-Host Disease
Rapamycin (RAPA) inhibits the mechanistic target of rapamycin (mTOR), a crucial immune system regulator. Dendritic cells (DC) generated in RAPA (RAPA-DC) enrich for CD4(+) forkhead box p3 (FoxP3(+)) regulatory T cells and induce T cell apoptosis by an unknown mechanism. RAPA-DC also promote experime...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964782/ https://ncbi.nlm.nih.gov/pubmed/24239650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.11.007 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|