Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins.
The effects of free polyunsaturated fatty acids (PUFA) on the binding of ligands to receptors on voltage-sensitive Na+ channels of neonatal rat cardiac myocytes were assessed. The radioligand was [benzoyl-2,5-(3)H] batrachotoxinin A 20alpha-benzoate ([(3)H]BTXB), a toxin that binds to the Na+ channe...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1996
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3542 |
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