Suppression of voltage-gated L-type Ca(2+ )currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes

Our recent data show that in cardiac myocytes polyunsaturated fatty acids (PUFAs) are antiarrhythmic. They reduce I(Na), shorten the action potential, shift the threshold for excitation to more positive potentials, and prolong the relative refractory period. In this study we use patch-clamp techniqu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Xiao, Yong-Fu, Gomez, Ana Maria, Morgan, James P., Lederer, W. J., Leaf, Alexander
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.4182
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