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Suppression of voltage-gated L-type Ca(2+ )currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes

Our recent data show that in cardiac myocytes polyunsaturated fatty acids (PUFAs) are antiarrhythmic. They reduce I(Na), shorten the action potential, shift the threshold for excitation to more positive potentials, and prolong the relative refractory period. In this study we use patch-clamp techniqu...

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Hlavní autoři: Xiao, Yong-Fu, Gomez, Ana Maria, Morgan, James P., Lederer, W. J., Leaf, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC20596/
https://ncbi.nlm.nih.gov/pubmed/9108126
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