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Effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on endothelial dysfunction, lipid peroxidation, and hepatocyte morphology in rats with sepsis-induced liver damage

BACKGROUND: Sepsis remains a difficult problem for clinicians, with its systemic effects and high morbidity and mortality rates. The roles of oxidative stress, endothelial dysfunction, and lipid peroxidation in sepsis-induced organ damage are being investigated. OBJECTIVE: The aim of this study was...

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Detalhes bibliográficos
Main Authors: Kara, Eray, Var, Ahmet, Vatansever, Seda, Cilaker, Serap, Kaya, Yavuz, Coşkun, Teoman
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964556/
https://ncbi.nlm.nih.gov/pubmed/24672083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0011-393X(04)80087-0
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