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Effects of silymarin and pentoxifylline on matrix metalloproteinase-1 and -2 expression and apoptosis in experimental hepatic fibrosis

Background: Many therapeutic strategies have been proposed to treat liver fibrosis, but no drugs have been proved effective. Matrix metalloproteinases (MMPs) have been reported to play a role in some cellular cascades of hepatic inflammation and fibrosis. Objective: The purpose of this study was to...

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Detalhes bibliográficos
Main Authors: Kara, Eray, Coşkun, Teoman, Kaya, Yavuz, Yumuş, Okan, Vatansever, Seda, Var, Ahmet
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969983/
https://ncbi.nlm.nih.gov/pubmed/24692823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2008.12.003
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