Protection against Lethal Enterovirus 71 Challenge in Mice by a Recombinant Vaccine Candidate Containing a Broadly Cross-Neutralizing Epitope within the VP2 EF Loop

Human enterovirus 71 (EV71) is the main causative agent of hand, foot, and mouth disease (HFMD) and is associated with several severe neurological complications in the Asia-Pacific region. Here, we evaluated that while passive transfer of neutralizing monoclonal antibody (nMAb) against the VP2 prote...

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Główni autorzy: Xu, Longfa, He, Delei, Li, Zhiqun, Zheng, Jun, Yang, Lisheng, Yu, Miao, Yu, Hai, Chen, Yixin, Que, Yuqiong, Shih, James Wai Kuo, Liu, Gang, Zhang, Jun, Zhao, Qinjian, Cheng, Tong, Xia, Ningshao
Format: Artigo
Język:Inglês
Wydane: Ivyspring International Publisher 2014
Hasła przedmiotowe:
Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964443/
https://ncbi.nlm.nih.gov/pubmed/24669278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.7457
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