In Vivo Time-Related Evaluation of a Therapeutic Neutralization Monoclonal Antibody against Lethal Enterovirus 71 Infection in a Mouse Model

Enterovirus 71 (EV71) is a neurotropic virus capable of inducing severe neurological symptoms and death. No direct targeting antivirals are useful in the treatment of severe EV71 infection. Because of low toxicity and good specificity, monoclonal antibodies (MAb) are a potential candidate for the tr...

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Main Authors: Li, Zhiqun, Xu, Longfa, He, Delei, Yang, Lisheng, Liu, Che, Chen, Yixin, Shih, James Wai Kuo, Zhang, Jun, Zhao, Qinjian, Cheng, Tong, Xia, Ningshao
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
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Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184856/
https://ncbi.nlm.nih.gov/pubmed/25279734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109391
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