Protection against Lethal Enterovirus 71 Challenge in Mice by a Recombinant Vaccine Candidate Containing a Broadly Cross-Neutralizing Epitope within the VP2 EF Loop

Human enterovirus 71 (EV71) is the main causative agent of hand, foot, and mouth disease (HFMD) and is associated with several severe neurological complications in the Asia-Pacific region. Here, we evaluated that while passive transfer of neutralizing monoclonal antibody (nMAb) against the VP2 prote...

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Detalhes bibliográficos
Main Authors: Xu, Longfa, He, Delei, Li, Zhiqun, Zheng, Jun, Yang, Lisheng, Yu, Miao, Yu, Hai, Chen, Yixin, Que, Yuqiong, Shih, James Wai Kuo, Liu, Gang, Zhang, Jun, Zhao, Qinjian, Cheng, Tong, Xia, Ningshao
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964443/
https://ncbi.nlm.nih.gov/pubmed/24669278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.7457
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