Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming

Somatic cell reprogramming toward induced pluripotent stem cells (iPSCs) holds great promise in future regenerative medicine. However, the reprogramming process mediated by the traditional defined factors (OSMK) is slow and extremely inefficient. Here, we develop a combination of modified reprogramm...

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Huvudupphovsmän: Zhu, Gengzhen, Li, Yujing, Zhu, Fei, Wang, Tao, Jin, Wensong, Mu, Wei, Lin, Wei, Tan, Weiqi, Li, Wenqi, Street, R. Craig, Peng, Siying, Zhang, Jian, Feng, Yue, Warren, Stephen T., Sun, Qinmiao, Jin, Peng, Chen, Dahua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964280/
https://ncbi.nlm.nih.gov/pubmed/24672749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.01.012
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