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β-Catenin Signaling Mediates CD4 Expression on Mature CD8(+) T Cells

Upon activation, a subset of mature human CD8(+) T cells re-expresses CD4 dimly. This CD4(dim)CD8(bright) T cell population is genuine and enriched in antiviral CD8(+) T cell responses. The signaling pathway that leads to CD4 re-expression on mature CD8(+) T cells is not clear. Given that Wnt/β-cate...

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Main Authors: Schenkel, Jason M., Zloza, Andrew, Li, Wei, Narasipura, Srinivas D., Al-Harthi, Lena
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963465/
https://ncbi.nlm.nih.gov/pubmed/20631314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902572
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