The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-renewal and Somatic Cell Reprogramming

Embryonic stem cell (ESC) self-renewal and differentiation are governed by a broad-ranging regulatory network. Although the transcriptional regulatory mechanisms involved have been investigated extensively, post-transcriptional regulation is still poorly understood. Here we describe a critical role...

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Autori principali: Wang, Li, Miao, Yi-liang, Zheng, Xiaofeng, Lackford, Brad, Zhou, Bingying, Han, Leng, Yao, Chengguo, Ward, James, Burkholder, Adam, Lipchina, Inna, Fargo, David C., Hochedlinger, Konrad, Shi, Yongsheng, Williams, Carmen J., Hu, Guang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962795/
https://ncbi.nlm.nih.gov/pubmed/24315442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.10.008
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