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Tissue-expressed B7x Affects the Immune Response and Outcome to Lethal Pulmonary Infection

B7x (B7-H4 or B7S1), a member of the B7 family, inhibits in vitro T cell proliferation and cytokine production by binding to an unidentified receptor on activated T cells, but its in vivo function remains largely unclear. We show that B7x protein was expressed in epithelial cells of the lung, but no...

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Bibliografiske detaljer
Main Authors: Hofmeyer, Kimberly A, Scandiuzzi, Lisa, Ghosh, Kaya, Pirofski, Liise-Anne, Zang, Xingxing
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962726/
https://ncbi.nlm.nih.gov/pubmed/22855708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200701
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