Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function

Obesity associated with metabolic derangements (ObM) worsens the prognosis of patients with coronary artery stenosis (CAS), but the underlying cardiac pathophysiologic mechanisms remain elusive. We tested the hypothesis that ObM exacerbates cardiomyocyte loss distal to moderate CAS. Obesity-prone pi...

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Autori principali: Li, Zi-Lun, Ebrahimi, Behzad, Zhang, Xin, Eirin, Alfonso, Woollard, John R., Tang, Hui, Lerman, Amir, Wang, Shen-Ming, Lerman, Lilach O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
Soggetti:
Integrative Cardiovascular Physiology and Pathophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962631/
https://ncbi.nlm.nih.gov/pubmed/24508639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00052.2013
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