Obesity-metabolic derangement preserves hemodynamics but promotes intrarenal adiposity and macrophage infiltration in swine renovascular disease

Obesity-metabolic disorders (ObM) often accompany renal artery stenosis (RAS). We hypothesized that the coexistence of ObM and RAS magnifies inflammation and microvascular remodeling in the stenotic kidney (STK) and aggravates renal scarring. Twenty-eight obesity-prone Ossabaw pigs were studied afte...

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Main Authors: Zhang, Xin, Li, Zi-Lun, Woollard, John R., Eirin, Alfonso, Ebrahimi, Behzad, Crane, John A., Zhu, Xiang-Yang, Pawar, Aditya S., Krier, James D., Jordan, Kyra L., Tang, Hui, Textor, Stephen C., Lerman, Amir, Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742861/
https://ncbi.nlm.nih.gov/pubmed/23657852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00043.2013
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