Obesity-metabolic derangement preserves hemodynamics but promotes intrarenal adiposity and macrophage infiltration in swine renovascular disease

Obesity-metabolic disorders (ObM) often accompany renal artery stenosis (RAS). We hypothesized that the coexistence of ObM and RAS magnifies inflammation and microvascular remodeling in the stenotic kidney (STK) and aggravates renal scarring. Twenty-eight obesity-prone Ossabaw pigs were studied afte...

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Autores principales: Zhang, Xin, Li, Zi-Lun, Woollard, John R., Eirin, Alfonso, Ebrahimi, Behzad, Crane, John A., Zhu, Xiang-Yang, Pawar, Aditya S., Krier, James D., Jordan, Kyra L., Tang, Hui, Textor, Stephen C., Lerman, Amir, Lerman, Lilach O.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742861/
https://ncbi.nlm.nih.gov/pubmed/23657852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00043.2013
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