Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function

Obesity associated with metabolic derangements (ObM) worsens the prognosis of patients with coronary artery stenosis (CAS), but the underlying cardiac pathophysiologic mechanisms remain elusive. We tested the hypothesis that ObM exacerbates cardiomyocyte loss distal to moderate CAS. Obesity-prone pi...

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Detalhes bibliográficos
Main Authors: Li, Zi-Lun, Ebrahimi, Behzad, Zhang, Xin, Eirin, Alfonso, Woollard, John R., Tang, Hui, Lerman, Amir, Wang, Shen-Ming, Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962631/
https://ncbi.nlm.nih.gov/pubmed/24508639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00052.2013
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