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Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2)
The phospholipase A(2) activity of peroxiredoxin 6 is inhibited by the transition state analog, 1-hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol (MJ33). This activity is required for the activation of NADPH oxidase, type 2. The present study evaluated the effect of MJ33 on manifestations...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962626/ https://ncbi.nlm.nih.gov/pubmed/24487388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00374.2013 |
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