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A systematic assessment of normalization approaches for the Infinium 450K methylation platform

The Illumina Infinium HumanMethylation450 BeadChip has emerged as one of the most popular platforms for genome wide profiling of DNA methylation. While the technology is wide-spread, systematic technical biases are believed to be present in the data. For example, this array incorporates two differen...

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Hlavní autoři: Wu, Michael C, Joubert, Bonnie R, Kuan, Pei-fen, Håberg, Siri E, Nystad, Wenche, Peddada, Shyamal D, London, Stephanie J
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962542/
https://ncbi.nlm.nih.gov/pubmed/24241353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27119
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