450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy

Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple adverse health outcomes in children, but the underlying mechanisms are unclear....

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Główni autorzy: Joubert, Bonnie R., Håberg, Siri E., Nilsen, Roy M., Wang, Xuting, Vollset, Stein E., Murphy, Susan K., Huang, Zhiqing, Hoyo, Cathrine, Midttun, Øivind, Cupul-Uicab, Lea A., Ueland, Per M., Wu, Michael C., Nystad, Wenche, Bell, Douglas A., Peddada, Shyamal D., London, Stephanie J.
Format: Artigo
Język:Inglês
Wydane: National Institute of Environmental Health Sciences 2012
Hasła przedmiotowe:
Research
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491949/
https://ncbi.nlm.nih.gov/pubmed/22851337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1205412
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