Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

Cervical cancer is a major health concern among women in Latin America due to its high incidence and mortality. Therefore, the discovery of molecular markers for cervical cancer screening and triage is imperative. The aim of this study was to use a genome wide DNA methylation approach to identify no...

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Detalhes bibliográficos
Main Authors: Brebi, Priscilla, Maldonado, Leonel, Noordhuis, Maartje G, Ili, Carmen, Leal, Pamela, Garcia, Patricia, Brait, Mariana, Ribas, Judit, Michailidi, Christina, Perez, Jimena, Soudry, Ethan, Tapia, Oscar, Guzman, Pablo, Muñoz, Sergio, Van Neste, Leander, Van Criekinge, Wim, Irizarry, Rafael, Sidransky, David, Roa, Juan C, Guerrero-Preston, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962541/
https://ncbi.nlm.nih.gov/pubmed/24241165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27120
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