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Post-Traumatic Hypoxia Is Associated with Prolonged Cerebral Cytokine Production, Higher Serum Biomarker Levels, and Poor Outcome in Patients with Severe Traumatic Brain Injury

Secondary hypoxia is a known contributor to adverse outcomes in patients with traumatic brain injury (TBI). Based on the evidence that hypoxia and TBI in isolation induce neuroinflammation, we investigated whether TBI combined with hypoxia enhances cerebral cytokine production. We also explored whet...

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Bibliographic Details
Main Authors: Yan, Edwin B., Satgunaseelan, Laveniya, Paul, Eldho, Bye, Nicole, Nguyen, Phuong, Agyapomaa, Doreen, Kossmann, Thomas, Rosenfeld, Jeffrey V., Morganti-Kossmann, Maria Cristina
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961772/
https://ncbi.nlm.nih.gov/pubmed/24279428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2013.3087
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