Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor

BACKGROUND: Diffuse axonal injury is a common consequence of traumatic brain injury (TBI) and often co-occurs with hypoxia, resulting in poor neurological outcome for which there is no current therapy. Here, we investigate the ability of the multifunctional compound erythropoietin (EPO) to provide n...

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Библиографические подробности
Главные авторы: Hellewell, Sarah C, Yan, Edwin B, Alwis, Dasuni S, Bye, Nicole, Morganti-Kossmann, M Cristina
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896698/
https://ncbi.nlm.nih.gov/pubmed/24344874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-156
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