Rab10-mediated Endocytosis of the Hyaluronan Synthase HAS3 Regulates Hyaluronan Synthesis and Cell Adhesion to Collagen

Hyaluronan synthases (HAS1–3) are unique in that they are active only when located in the plasma membrane, where they extrude the growing hyaluronan (HA) directly into cell surface and extracellular space. Therefore, traffic of HAS to/from the plasma membrane is crucial for the synthesis of HA. In t...

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Bibliographische Detailangaben
Hauptverfasser: Deen, Ashik Jawahar, Rilla, Kirsi, Oikari, Sanna, Kärnä, Riikka, Bart, Genevieve, Häyrinen, Jukka, Bathina, Avinash Rahul, Ropponen, Antti, Makkonen, Katri, Tammi, Raija H., Tammi, Markku I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961663/
https://ncbi.nlm.nih.gov/pubmed/24509846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.552133
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