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Cytochrome P450 2C Epoxygenases Mediate Photochemical Stress-induced Death of Photoreceptors

Degenerative loss of photoreceptors occurs in inherited and age-related retinal degenerative diseases. A chemical screen facilitates development of new testing routes for neuroprotection and mechanistic investigation. Herein, we conducted a mouse-derived photoreceptor (661W cell)-based high throughp...

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Detalhes bibliográficos
Main Authors: Chang, Qing, Berdyshev, Evgeny, Cao, Dingcai, Bogaard, Joseph D., White, Jerry J., Chen, Siquan, Shah, Ravi, Mu, Wenbo, Grantner, Rita, Bettis, Sam, Grassi, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961660/
https://ncbi.nlm.nih.gov/pubmed/24519941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507152
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