3-Deazaneplanocin A (DZNep), an Inhibitor of S-Adenosylmethionine-dependent Methyltransferase, Promotes Erythroid Differentiation

EZH2, a core component of polycomb repressive complex 2 (PRC2), plays a role in transcriptional repression through histone H3 Lys-27 trimethylation and is involved in various biological processes, including hematopoiesis. It is well known that 3-deazaneplanocin A (DZNep), an inhibitor of S-adenosylm...

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Bibliografski detalji
Glavni autori: Fujiwara, Tohru, Saitoh, Haruka, Inoue, Ai, Kobayashi, Masahiro, Okitsu, Yoko, Katsuoka, Yuna, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Ichinohasama, Ryo, Harigae, Hideo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Gene Regulation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961643/
https://ncbi.nlm.nih.gov/pubmed/24492606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548651
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