MITOCHONDRIA-TARGETED ANTIOXIDANTS FOR TREATMENT OF PARKINSON’S DISEASE: PRECLINICAL AND CLINICAL OUTCOMES

Parkinson’s disease (PD) is a progressive neurodegenerative disease in the elderly, and no cure or disease-modifying therapies exist. Several lines of evidence suggest that mitochondrial dysfunction and oxidative stress have a central role in the dopaminergic neurodegeneration of PD. In this context...

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Main Authors: Jin, Huajun, Kanthasamy, Arthi, Ghosh, Anamitra, Anantharam, Vellareddy, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961561/
https://ncbi.nlm.nih.gov/pubmed/24060637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.09.007
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