Vaccination against Endogenous Retrotransposable Element Consensus Sequences Does Not Protect Rhesus Macaques from SIVsmE660 Infection and Replication

The enormous sequence diversity of HIV remains a major roadblock to the development of a prophylactic vaccine and new approaches to induce protective immunity are needed. Endogenous retrotransposable elements (ERE) such as endogenous retrovirus K (ERV)-K and long interspersed nuclear element-1 (LINE...

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Autores principales: Sheppard, Neil C., Jones, R. Brad, Burwitz, Benjamin J., Nimityongskul, Francesca A., Newman, Laura P., Buechler, Matthew B., Reed, Jason S., Piaskowski, Shari M., Weisgrau, Kim L., Castrovinci, Philip A., Wilson, Nancy A., Ostrowski, Mario A., Park, Byung, Nixon, Douglas F., Rakasz, Eva G., Sacha, Jonah B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961289/
https://ncbi.nlm.nih.gov/pubmed/24651676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092012
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