Vaccination against Endogenous Retrotransposable Element Consensus Sequences Does Not Protect Rhesus Macaques from SIVsmE660 Infection and Replication

The enormous sequence diversity of HIV remains a major roadblock to the development of a prophylactic vaccine and new approaches to induce protective immunity are needed. Endogenous retrotransposable elements (ERE) such as endogenous retrovirus K (ERV)-K and long interspersed nuclear element-1 (LINE...

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Bibliographic Details
Main Authors: Sheppard, Neil C., Jones, R. Brad, Burwitz, Benjamin J., Nimityongskul, Francesca A., Newman, Laura P., Buechler, Matthew B., Reed, Jason S., Piaskowski, Shari M., Weisgrau, Kim L., Castrovinci, Philip A., Wilson, Nancy A., Ostrowski, Mario A., Park, Byung, Nixon, Douglas F., Rakasz, Eva G., Sacha, Jonah B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961289/
https://ncbi.nlm.nih.gov/pubmed/24651676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092012
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