End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging

There is growing evidence that stochastic events play an important role in determining individual longevity. Studies in model organisms have demonstrated that genetically identical populations maintained under apparently equivalent environmental conditions display individual variation in lifespan th...

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Main Authors: Delaney, Joe R., Chou, Annie, Olsen, Brady, Carr, Daniel, Murakami, Christopher, Ahmed, Umema, Sim, Sylvia, An, Elroy H., Castanza, Anthony S., Fletcher, Marissa, Higgins, Sean, Holmberg, Mollie, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Moller, Richard, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Schleit, Jennifer, Schuster, Alex, Singh, Minnie, Spector, Benjamin L., Sutphin, George L., Wang, Adrienne M., Wasko, Brian M., Wende, Helen Vander, Kennedy, Brian K., Kaeberlein, Matt
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960949/
https://ncbi.nlm.nih.gov/pubmed/23336757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1567-1364.12030
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