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EpCAM modulates nuclear factor-κB signaling and interleukin-8 expression in breast cancer

EpCAM is a 40-kD type I transmembrane protein that is overexpressed in human epithelial cancers, and is currently the target of molecular therapy based on its overexpression at the cell surface. Recently, we and others have demonstrated a role for EpCAM in cell signaling and carcinogenesis, and EpCA...

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Hlavní autoři: Sankpal, NV, Fleming, TP, Gillanders, WE
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960600/
https://ncbi.nlm.nih.gov/pubmed/23378578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0518
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