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EpCAM modulates nuclear factor-κB signaling and interleukin-8 expression in breast cancer

EpCAM is a 40-kD type I transmembrane protein that is overexpressed in human epithelial cancers, and is currently the target of molecular therapy based on its overexpression at the cell surface. Recently, we and others have demonstrated a role for EpCAM in cell signaling and carcinogenesis, and EpCA...

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Библиографические подробности
Главные авторы: Sankpal, NV, Fleming, TP, Gillanders, WE
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960600/
https://ncbi.nlm.nih.gov/pubmed/23378578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0518
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