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Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise

The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. With the purpose of identifying potential epigenetic markers involved in aging and neurodegeneration, here we analyzed the expression of 84 mature miRNAs, the expression of histone-acety...

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Detalhes bibliográficos
Main Authors: Cosín-Tomás, Marta, Alvarez-López, María J., Sanchez-Roige, Sandra, Lalanza, Jaume F., Bayod, Sergi, Sanfeliu, Coral, Pallàs, Merce, Escorihuela, Rosa M., Kaliman, Perla
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960508/
https://ncbi.nlm.nih.gov/pubmed/24688469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00051
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