Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline

A growing body of research shows that epigenetic mechanisms are critically involved in normal and pathological aging. The Senescence-Accelerated Mouse Prone 8 (SAMP8) can be considered a useful tool to better understand the dynamics of the global epigenetic landscape during the aging process since i...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Cosín-Tomás, Marta, Álvarez-López, María Jesús, Companys-Alemany, Júlia, Kaliman, Perla, González-Castillo, Celia, Ortuño-Sahagún, Daniel, Pallàs, Mercè, Griñán-Ferré, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297390/
https://ncbi.nlm.nih.gov/pubmed/30619445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00596
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