Extended Wakefulness: Compromised Metabolics in and Degeneration of Locus Ceruleus Neurons

Modern society enables a shortening of sleep times, yet long-term consequences of extended wakefulness on the brain are largely unknown. Essential for optimal alertness, locus ceruleus neurons (LCns) are metabolically active neurons that fire at increased rates across sustained wakefulness. We hypot...

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Detalhes bibliográficos
Main Authors: Zhang, Jing, Zhu, Yan, Zhan, Guanxia, Fenik, Polina, Panossian, Lori, Wang, Maxime M., Reid, Shayla, Lai, David, Davis, James G., Baur, Joseph A., Veasey, Sigrid
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960479/
https://ncbi.nlm.nih.gov/pubmed/24647961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5025-12.2014
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