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SIRT1 Regulation of Wakefulness and Senescence-Like Phenotype in Wake Neurons
Wake neurons in the basal forebrain and brainstem provide critical inputs to optimize alertness and attention. These neurons, however, evidence heightened vulnerability to a diverse array of metabolic challenges, including aging. SIRT1 is an nicotinamide adenine dinucleotide responsive deacetylase s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065120/ https://ncbi.nlm.nih.gov/pubmed/21411645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5166-10.2011 |
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