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Effects of Chronic Sleep Fragmentation on Wake-Active Neurons and the Hypercapnic Arousal Response

STUDY OBJECTIVES: Delayed hypercapnic arousals may occur in obstructive sleep apnea. The impaired arousal response is expected to promote more pronounced oxyhemoglobin desaturations. We hypothesized that long-term sleep fragmentation (SF) results in injury to or dysfunction of wake-active neurons th...

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Detalhes bibliográficos
Main Authors: Li, Yanpeng, Panossian, Lori A., Zhang, Jing, Zhu, Yan, Zhan, Guanxia, Chou, Yu-Ting, Fenik, Polina, Bhatnagar, Seema, Piel, David A., Beck, Sheryl G., Veasey, Sigrid
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902866/
https://ncbi.nlm.nih.gov/pubmed/24470695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.3306
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