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Sepantronium is a DNA damaging agent that synergizes with PLK1 inhibitor volasertib

In a search for novel agents that boost the anti-neoplastic effects of polo-like kinase 1 (PLK1) inhibitor volasertib, we found that a sepantronium and volasertib combination at the nano mole concentration potently inhibited growth of various non-small cell lung cancer (NSCLC) cell lines than either...

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Autors principals: Hong, Mei, Ren, Mingqiang, Silva, Jeane, Kennedy, Thomas, Choi, Justin, Cowell, John K, Hao, Zhonglin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960451/
https://ncbi.nlm.nih.gov/pubmed/24660103
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